Tumores malignos de glándulas salivales: Serie de casos de tres centros de alto volumen de la Argentina

Federico Cayol; Inés Pucella; Pilar Tilot; Albano Blanco; Vanesa Kazanietz; Sergio Specterman; Agustín Falco; Gonzalo Gómez Auin

doi:10.56969/oc.v24i2.40

Autores/as

Federico Cayol Sección de Oncología Clínica, Hospital Italiano de Buenos Aires https://orcid.org/0000-0001-9794-2173
Inés Pucella Sección de Oncología, Hospital Italiano de Buenos Aires
Pilar Tilot Servicio de Oncología, Hospital Alemán
Albano Blanco Instituto Alexander Fleming, Buenos Aires https://orcid.org/0000-0002-1665-5373
Vanesa Kazanietz Sección de Oncología, Hospital Italiano de Buenos Aires
Sergio Specterman Sección Oncología, Hospital Italiano de Buenos Aires
Agustín Falco Instituto Alexander Fleming, Buenos Aires https://orcid.org/0000-0003-4487-2444
Gonzalo Gómez Auin Servicio de Oncología, Hospital Alemán

DOI:

https://doi.org/10.56969/oc.v24i2.40

Palabras clave:

tumores malignos, glándulas salivales, histologías, tratamientos, cirugía, radioterapia adyuvante, malignant tumors, salivary glands, histologies, treatments, surgery, adjuvant radiotherapy

Resumen

Los tumores de glándulas salivales son relativamente poco frecuentes, presentanm histologías y comportamiento clínico muy variado, lo cual dificulta su estudio.

El propósito de este estudio fue describir la experiencia en cuanto al tratamiento de estos tumores en un estudio multi-institucional.

Se realizó un estudio retrospectivo, en tres instituciones de alto volumen de pacientes, de la ciudad de Buenos Aires, Argentina. Se analizaron las características clínicas, histológicas y primeros tratamientos realizados en los pacientes con tumores malignos de glándulas salivales. Se analizaron la supervivencia libre de enfermedad y supervivencia global con curvas de Kaplan Meier.

La localización encontrada con más frecuencia fue la parótida, los tipos histológicos predominantes fueron el carcinoma mucoepidermoide y carcinoma adenoideo quístico. La cirugía fue el tratamiento más frecuentemente realizado y la radioterapia adyuvante se utilizó en 74% de los casos. En el subgrupo de pacientes operados la supervivencia libre de enfermedad mediana fue de 134 meses (r 38.5-230.1) y la supervivencia global no fue alcanzada.

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